Glossary entry

English term or phrase:

helix-distorting lesions

Croatian translation:

lezije/oštećenja koja iskrivljuju heliks

    The asker opted for community grading. The question was closed on 2010-12-25 13:54:10 based on peer agreement (or, if there were too few peer comments, asker preference.)
Dec 22, 2010 12:52
13 yrs ago
English term

helix-distorting lesions

English to Croatian Medical Medical (general) molecular microbiology
Poštovane kolege, molim vas za savjet u pogledu prijevoda navedenog termina. Naime, pretpostavljam da se radi o lezijama koje iskrivljuju (narušavaju??) spiralu, no nisam posve siguran da li se ovdje prevodi kao heliks, spirala ili nešto treće. Obzirom da nisam siguran, smatram da je najbolje da se posavjetujem sa vama.
Konteksti su slijedeći:

1. XPC-RAD23B has been shown in vitro to bind better
to duplex DNA containing helix-distorting lesions, such as
cisplatin adducts, compared to undamaged DNA

2. This increased recognition of more helix-distorting lesions has
also been observed in examination of 1,3 GpXpG vs. 1,2
GpG cisplatin-DNA adducts.

3. DNA and has been shown to
induce the first structural changes in the DNA required for
NER, specifically the opening of the DNA double helix

Hvala.
Proposed translations (Croatian)
4 lezije/oštećenja koja iskrivljuju heliks

Proposed translations

8 mins
Selected

lezije/oštećenja koja iskrivljuju heliks

možete reći heliks, uzvojnica humane DNK je dvostruki heliks.
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4 KudoZ points awarded for this answer. Comment: "Hvala! Evo i bodova!"
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